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If not properly considered, managed, and overseen, the use of certain chemicals can result in conditions of higher risk for laboratory personnel and to facilities. The approval of the PI or Laboratory Supervisor is required when certain Restricted Chemicals that carry a higher risk due to their inherent hazardous property are used in Stanford laboratories. Laboratory personnel may not use Restricted Chemicals in any Stanford laboratory without obtaining the prior written approval of the PI or his/her delegate. See Section 5.0 for more information.