Use of some animal tissues requires an APLAC protocol due to occupational health concerns, even if the tissues are a by-product of another APLAC-approved studies, are obtained from a slaughterhouse, or are commercially available as standard “off-the-shelf” products. In general, this includes cells or tissues from non-human primates or other RC1 category animals, such as sheep. To determine if your use of tissue requires a protocol, please contact APLAC. If it is confirmed you will need a protocol, you can file a tissue-only protocol. Contact APLAC for protocol determination and requirements.