All vectors are not the same. More importantly, the class of gene insert can change the Biosafety level of the construct. It is also important to realize that obtaining a cloning/expression vector from a commercial source does not mean it is automatically exempt or a BSL – 1. Table 3 lists many of the more common viral vectors in combination with different classes of inserts and their associated BSL level.
Important Information
Viral Vector Inserts and Envelopes
Some inserts such as oncogenes or toxins will raise the biosafety containment level of the viral vector (See Table 3); the same is true for certain envelopes.
