How to use this tool
The radiation doses to the fetus at various points in gestation for a number of diagnostic nuclear medicine studies are tabulated below. “Early” refers to irradiation during the first portion of the first trimester; “Months 3, 6 and 9” to irradiation at the ends of the first, second and third trimesters respectively. The doses are expressed in millirads, and assume an amount of administered radioactivity which is customary for the study. When an agent has several indications using different administered activities, the highest value is assumed.
Studies for which values appear in bold can carry an increased risk. Please refer to the Exposure to X-Rays and Nuclear Medicine Studies During Pregnancy subtopic for more information.
The information supplied for I-131 sodium iodide and I-131 MIBG is for diagnostic studies. Therapeutic procedures with these radiopharmaceuticals incur far higher doses and require special computational treatment.
| Radiopharmaceutical | Early | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Co-57 Vitamin B-1 Normal-Flushing | 4 | 3 | 3 | 4 |
| Co-57 Vitamin B-12 Normal-No Flushing | 6 | 4 | 5 | 5 |
| Co-57 Vitamin B-12 PA- Flushing | 1 | 1 | 1 | 1 |
| Co-57 Vitamin B-12 PA- No Flushing | 1 | 1 | 1 | 1 |
| Co-58 Vitamin B-12 Normal-Flushing | 8 | 6 | 6 | 6 |
| Co-58 Vitamin B-12 Normal-No Flushing | 11 | 8 | 9 | 9 |
| Co-58 Vitamin B-12 PA-Flushing | 2 | 2 | 2 | 1 |
| Co-58 Vitamin B-12 PA-No Flushing | 3 | 3 | 2 | 2 |
| F-18 FDG | 999 | 629 | 348 | 300 |
| Ga-67 Citrate | 1767 | 3800 | 3420 | 2470 |
| I-123 Hippuran | 233 | 180 | 63 | 59 |
| I-123 IMP | 380 | 220 | 142 | 118 |
| I-123 MIBG | 630 | 420 | 238 | 217 |
| I-123 Sodium Iodide | 60 | 42 | 33 | 29 |
| I-125 HSA | 50 | 16 | 8 | 5 |
| I-125 Sodium Iodide | 2 | 1 | < 1 | < 1 |
| I-131 HSA | 26 | 9 | 8 | 7 |
| I-131 MAA | 369 | 231 | 220 | 231 |
| I-131 MIBG | 220 | 108 | 76 | 70 |
| I-131 Rose Bengal | 1 | 1 | 1 | <1 |
| I-131 Sodium Iodide | 288 | 272 | 920 | 1080 |
| In-111 DTPA | 130 | 96 | 40 | 36 |
| In-111 Pentetreotide | 1886 | 1380 | 805 | 713 |
| In-111 Platelets | 170 | 110 | 99 | 89 |
| In-111 White Blood Cells | 260 | 192 | 192 | 188 |
| Tc-99m Disofenin | 595 | 525 | 420 | 235 |
| Tc-99m DMSA | 112 | 103 | 88 | 75 |
| Tc-99m DTPA | 900 | 653 | 308 | 353 |
| Tc-99m DTPA Aerosol | 23 | 17 | 9 | 12 |
| Tc-99m Glucoheptonate | 900 | 825 | 398 | 345 |
| Tc-99m HDP | 390 | 405 | 225 | 188 |
| Tc-99m HMPAO | 653 | 503 | 360 | 270 |
| Tc-99m Human Serum Albumin | 102 | 60 | 52 | 44 |
| Tc-99m MAA | 62 | 88 | 110 | 88 |
| Tc-99m MAG3 | 1350 | 1050 | 413 | 390 |
| Tc-99m MDP | 458 | 405 | 203 | 180 |
| Tc-99m MIBI-rest | 1650 | 1320 | 924 | 594 |
| Tc-99m MIBI-stress | 1320 | 1045 | 759 | 484 |
| Tc-99m Pertechnetate | 1210 | 2420 | 1540 | 1023 |
| Tc-99m PYP | 420 | 462 | 252 | 203 |
| Tc-99m RBC-in vitro | 632 | 437 | 316 | 260 |
| Tc-99m RBC-in vivo | 595 | 400 | 307 | 251 |
| Tc-99m Sulfur Colloid-Liver Disease | 144 | 113 | 126 | 126 |
| Tc-99m Sulfur Colloid-normal | 81 | 95 | 144 | 167 |
| Tc-99m White Blood Cells | 76 | 56 | 58 | 56 |
| Tl-201 Chloride | 1455 | 870 | 705 | 405 |
| Xe-133 5 minute rebreathing 10 liter spirometer volume | 19 | 2 | 2 | 1 |
| Xe-133 5 minute rebreathing 5 liter spirometer volume | 31 | 4 | 3 | 2 |
| Xe-133 5 minute rebreathing 7.5 liter spirometer volume | 17 | 2 | 1 | 1 |
| Xe-133 injection | 1 | < 1 | < 1 | < 1 |
