mechanical device Only mechanical device Only mechanical device Only mechanical device HEPA-filtered vacuum lines Recommended Required Required Required *Procedures include but not limited to: centrifuging

combinations of special protective clothing plus NIOSH N95 respirators or equivalent for all activities with biohazardous materials Biological Safety Cabinet (BSC) Not required Required for all aerosol generated

The BSL categories are divided up by risk of disease combined with availability of preventive and therapeutic treatments. The four groups are shown in Table 1.

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