A BSC air curtain is very delicate and provides the only barrier between the inside (potentially infectious aerosols) and the outside (where personnel are) air. Air-flow turbulence from both inside and outside of the BSC risks breach of containment; as such, cabinets should be located away from doors, high traffic areas and building HVAC systems (vents). The Biosafety program can assist in evaluating the best placement for a BSC to protect both the material and the researchers.